NaturaMatch™

Natural Compound Response Profiling

NaturaMatch™ is an advanced personalized cancer-cell response profiling test designed to evaluate how an individual patient’s cancer cells respond to selected natural substances and plant-derived compounds.

Cancer biology can vary significantly between individuals. A natural compound that appears relevant for one patient may show a very different response in another. NaturaMatch™ provides laboratory-based information using the patient’s own circulating tumour cells to help healthcare professionals make more informed decisions when considering natural compounds as part of a professionally supervised integrative oncology plan.

Rather than selecting supplements based only on general recommendations, NaturaMatch™ provides a more personalized approach based on the biological response of the individual patient’s cancer cells.

Two levels of testing are available:

• NaturaMatch™ Standard: Natural Compound Response Profiling
• NaturaMatch Molecular™ Advanced: Natural Compound & Molecular Profiling

WHAT NATURAMATCH™ IS?

NaturaMatch™ is a blood-based cancer-cell response profiling test designed for individuals with an established cancer diagnosis.

The test isolates circulating tumour cells, also known as CTCs, from the patient's blood and evaluates how these cells respond when exposed to a broad panel of selected natural substances and plant extracts.

More than 50 selected natural compounds may be evaluated across different functional categories, including compounds studied for direct cellular effects, immune-related activity and cellular signalling pathways.

The test also provides information on the patient's circulating tumour cell count.

The results are intended to support professional treatment planning and should not be interpreted as a guarantee that a particular supplement or compound will produce the same effect inside the body.

HOW NATURAMATCH™ WORKS?

The process begins with a professionally collected blood sample.

Circulating tumour cells are isolated from the sample and used for laboratory response testing.

Selected natural substances and plant extracts are then evaluated against the patient's cancer cells to observe how the cells respond under controlled laboratory conditions.

The general process includes:

1. Doctor consultation and suitability assessment
2. Professional blood sample collection
3. Isolation of circulating tumour cells
4. Laboratory testing against selected natural compounds
5. Comparative response analysis
6. Report generation
7. Doctor-led interpretation
8. Personalized integrative oncology planning

For selected central nervous system primary tumours, an appropriate tissue sample may be required instead of a standard peripheral blood sample.

CHOOSE YOUR NATURAMATCH™ VARIANT

NaturaMatch™ Standard

Designed for patients who primarily want to understand which selected natural substances and plant extracts demonstrate stronger or weaker responses against their cancer cells.

The Standard profile includes:

• Circulating tumour cell assessment
• Response profiling against more than 50 selected natural substances and plant extracts
• Comparative evaluation of compound response
• Information to support doctor-led selection of appropriate complementary compounds

NaturaMatch Molecular™ Advanced

NaturaMatch Molecular™ includes the core natural-compound response profiling available in NaturaMatch™, with an additional layer of molecular cancer-cell analysis.

The Advanced profile includes:

• Circulating tumour cell assessment
• Response profiling against more than 50 selected natural substances and plant extracts
• Gene-expression profiling of the patient's cancer cells
• Assessment of cancer-cell resistance-related factors
• Deeper molecular information to support individualized treatment planning

This provides additional insight not only into which compounds demonstrate a response, but also into selected molecular characteristics of the patient's cancer cells.

The Advanced option is therefore designed for patients and doctors who require a more comprehensive biological picture.

WHAT MAKES NATURAMATCH™ DIFFERENT?

• Tests the Patient's Own Cancer Cells
  • NaturaMatch™ does not rely solely on generalized population-level recommendations. It evaluates selected compounds against cancer cells isolated from the individual patient.
• Personalized Natural Compound Profiling
  • Different patients may demonstrate different cellular responses to the same compound. NaturaMatch™ helps identify these individual differences.
• Broad Natural Compound Panel
  • The laboratory evaluates more than 50 selected natural substances and plant extracts rather than focusing on only one or two supplements.
• Includes Circulating Tumour Cell Assessment
  • CTC information provides an additional biological reference alongside the compound-response findings.
• Standard and Advanced Options
  • Patients can select focused natural-compound profiling or a more comprehensive molecular version depending on the level of information required.
• Supports Integrative Oncology Planning
  • The findings provide additional laboratory information that a doctor may consider together with conventional cancer treatment, medical history, medications and the patient's overall clinical condition.

KEY BENEFITS

• Reduces Guesswork
  • Helps move natural-compound selection away from a purely trial-and-error approach.
• Provides Individualized Information
  • Evaluates laboratory response using cancer cells obtained from the individual patient.
• Compares Multiple Natural Compounds
  • Allows healthcare professionals to review relative responses across a broad panel of selected substances.
• Supports More Focused Supplement Planning
  • May help reduce unnecessary use of compounds showing limited relevance within the laboratory assessment.
• Complements Conventional Cancer Care
  • The information may be incorporated into a broader, doctor-supervised oncology strategy rather than being used as a replacement for established cancer treatment.
• Offers Deeper Molecular Insight
  • NaturaMatch Molecular™ provides additional gene-expression and resistance-related information for patients requiring a more advanced cancer-cell profile.

WHO NATURAMATCH™ IS DESIGNED FOR?

NaturaMatch™ may be considered for individuals who:

• have an established cancer diagnosis
• are considering natural compounds as part of an integrative oncology program
• are already taking multiple supplements and want a more structured approach
• want laboratory-based information to support natural-compound selection
• want to complement conventional oncology care with personalized biological information
• require additional information after previous treatment
• want to reduce unnecessary trial-and-error when considering complementary compounds
• have been advised by their treating doctor to undertake personalized cancer-cell response profiling

NaturaMatch Molecular™ may be particularly relevant when deeper information about cancer-cell gene expression and resistance characteristics is required.

IMPORTANT NOTICE

NaturaMatch™ and NaturaMatch Molecular™ are personalized laboratory response-profiling tests intended to provide additional information for professional cancer-care planning.

They are not standalone diagnostic tests and are not intended to independently diagnose, treat, cure or prevent cancer.

A laboratory response to a natural substance does not guarantee that the same response will occur clinically within the patient's body.

Natural substances and supplements may interact with chemotherapy, radiotherapy, targeted therapy, immunotherapy, hormonal treatment, prescription medications or other medical interventions.

All results must therefore be interpreted by appropriately qualified healthcare professionals together with the patient's diagnosis, medical history, current treatment and overall clinical condition.

NaturaMatch™ is intended to support informed clinical decision-making, not replace established cancer treatment or professional medical judgement.